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The ActiPix™ SDI300 from Paraytec - The World's first Surface Dissolution Imaging System
11.11.2009

ActiPix™ SDI300 from Paraytec - the World's first Surface Dissolution Imaging System

The ActiPix™ SDI300 from Paraytec is the world's first Surface Dissolution Imaging System. For the first time scientists can now directly image surface dissolution processes to enable a better mechanistic of dissolution processes as it enables quantitative imaging of surface phenomena for a diverse range of substances including active pharmaceutical ingredients (APIs), tablets, formulations, gels, liquids, suspensions, stents and patches.
 
Used as a tool for accelerated pre-formulations development, the SDI300 is proven to enable intrinsic dissolution rates to be obtained in less than 20 minutes, a fraction of the time compared to conventional dissolution systems. The dissolution medium can easily be exchanged, e.g. from 0.1 M HCl, to a neutral buffer, or to an aqueous alcoholic solution.
 
Compact in design, the SDI300 system includes award-winning ActiPix UV area imaging technology, a surface dissolution imaging sample holder, an integrated syringe pump, and software which enables real time quantitative recording and review of data. The SDI300 uses a highly sensitive UV area imaging sensor to record, interrogate and analyse a variety of complex processes.

With its automated software for direct visualization and analysis of the dissolution process, the SDI300 is a flexible, easy to use, multipurpose UV imaging tool which is ideal for investigating the dissolution and release in drug processes in a higher level of detail than before.

The ActiPix™ SDI300 Dissolution Imager can also be used for other applications such as monitoring the rate of diffusion of species through membranes as well as to provide fundamental information of amorphous to crystalline transformations. It can be placed in a temperature controlled environment, for example to simulate physiological conditions.

The SDI300 is available in Germany, Austria, Switzerland, Denmark and France from Zinsser Analytic GmbH.

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