Automated Laboratory High Throughput Solid Phase Extraction

Fully automated solid phase extraction for various applications.

Analysis of Contaminants

Zinsser Analytic invented a new automated system with different solid phase extraction (SPE) methods for various applications. The system does solid phase extraction for analysis of the following contaminants:

  • Acrylamide
  • Cyanuric acid
  • Aflatoxin M1
  • Melamine
  • Aflatoxin B/G
  • Ochratoxin

With our SPE system you will achieve:

  • Reproducible and reliable results
  • Increased throughput
  • Simplified and precise sample handling
  • Unique variation of SPE methods

High Throughput Solid Phase Application

High Throughput Solid Phase Application


  1. Robotic arm with 4 standard tips and gripper for racks.
  2. Source rack with 24 positions of prepared sample solution.
  3. Solvent rack for frequently used solvents, which are not system liquids.
  4. Pick up pressure spots for applying positive pressure to the cartridges.
  5. Conditioning and park tray for cartridges
  6. Elution position for cartridges into desired vials.
  7. Syringe pumps with 6-way-valves
  8. Cartridge rack park.

High Throughput Solid Phase Application

Automatable Processes

The automated high throughput SPE system can perform different SPE methods as per the protocols for the analytes.

As an example the acrylamide and cyanuric acid SPE processes are shown below. The solvent can either be processed through gravity based drip through or pushed through the cartridge with positive pressure, pulsed positive pressure or with vacuum supported suction. Single run (e.g. cyanuric acid) and multiple run (e.g. acrylamide) of SPE is possible with pipetting out of the first collection vessels into the new cartridges.

Between 24 and 48 SPE columns can be processed in one run.

A throughput of 92 to 384 samples within a working day (8 h) is possible.